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Geneviève M. C. Gasmi-Seabrook

Princess Margaret Cancer Centre

22

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836

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Oncogenic KRAS G12D mutation promotes dimerization through a second, phosphatidylserine–dependent interface: a model for KRAS oligomerization

2021 Chemical Science
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Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry.

2021 Nature Communications
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NMR-driven structure of the KRAS4B-G12D ""alpha-alpha"" dimer on a lipid bilayer nanodisc

2021
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Two Distinct Structures of Membrane‐associated Homodimers of GTP‐ and GDP‐bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement

2020 Angewandte Chemie
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NMR in integrated biophysical drug discovery for RAS: past, present, and future.

2020 Journal of Biomolecular NMR
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Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane.

2020 Proceedings of the National Academy of Sciences of the United States of America
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NMR-driven structure of KRAS4B-GTP homodimer on a lipid bilayer nanodisc

2020
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NMR data-driven model of KRas-GMPPNP:RBD-CRD complex tethered to a nanodisc (state A)

2020
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Evolution of AF6-RAS association and its implications in mixed-lineage leukemia

2017 Nature Communications
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Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1)

2016 Journal of Biological Chemistry
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