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Denis Martin

Drugs for Neglected Diseases Initiative

9

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Development of a Scalable Process for the Synthesis of DNDI-VL-2098: A Potential Preclinical Drug Candidate for the Treatment of Visceral Leishmaniasis

2017 Organic Process Research & Development
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Repositioning Antitubercular 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazoles for Neglected Tropical Diseases: Structure-Activity Studies on a Preclinical Candidate for Visceral Leishmaniasis.

2016 Journal of Medicinal Chemistry
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Nitroimidazo-oxazole compound DNDI-VL-2098: an orally effective preclinical drug candidate for the treatment of visceral leishmaniasis

2015 Journal of Antimicrobial Chemotherapy
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Aminothiazoles: Hit to lead development to identify antileishmanial agents.

2015 European Journal of Medicinal Chemistry
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Design, synthesis, ADME characterization and antileishmanial evaluation of novel substituted quinoline analogs

2014 Bioorganic & Medicinal Chemistry Letters
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In vitro metabolism, disposition, preclinical pharmacokinetics and prediction of human pharmacokinetics of DNDI-VL-2098, a potential oral treatment for Visceral Leishmaniasis

2014 European Journal of Pharmaceutical Sciences
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Poly(methacrylic acid) complexation of amphotericin B to treat neglected diseases

2014 Polymer Chemistry
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An Improved Kilogram-Scale Synthesis of 2-Bromo-4-nitro-1H-imidazole: A Key Building Block of Nitroimidazole Drugs

2013 Organic Process Research & Development
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Design, synthesis and biological evaluation of 2-substituted quinolines as potential antileishmanial agents.

2013 European Journal of Medicinal Chemistry
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