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Fumihiko Nakao

Kyushu University

8

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24

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Targeting leukemia-specific dependence on the de novo purine synthesis pathway.

2021 Leukemia
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Genome-wide CRISPR-Cas9 screen identifies rationally designed combination therapies for CRLF2- rearranged Ph-like ALL

2021 Blood
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CRISPR-Cas9 Screen Identifies XPO7 As a Potential Therapeutic Target for TP53 -Mutated AML

2019 Blood
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CRISPR-Cas9 Screen Identifies XPO7 as a Novel Therapeutic Target for TP53-Mutated AML

2019 Clinical Lymphoma, Myeloma & Leukemia
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CRISPR-Cas9 Screen Identifies Me2 , a Mitochondrial Malic Enzyme, As a Molecule Relevant for MCL1 Inhibitor Resistance in AML

2019 Blood
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Genome-Wide CRISPR Screen Identifies PAICS, An Enzyme Involved in De Novo Purine Synthesis, As a Potential Target for AML Therapy

2019 Clinical Lymphoma, Myeloma & Leukemia
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Paics, a De Novo Purine Synthetic Enzyme, Is a Novel Target for AML Therapy

2019 Blood
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Protein-bound polysaccharide decreases invasiveness and proliferation in pancreatic cancer by inhibition of hedgehog signaling and HIF-1α pathways under hypoxia

2013 Cancer Letters
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