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Dagart Allison
Dagart Allison
Chemistry
Biochemistry
NAD+ kinase
Prostaglandin E2
Enzyme
3
Papers
179
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Crystal Structures of mPGES-1 Inhibitor Complexes Form a Basis for the Rational Design of Potent Analgesic and Anti-Inflammatory Therapeutics.
2015
Journal of Medicinal Chemistry
John G. Luz
Stephen Antonysamy
Steven Lee Kuklish
Bradley Condon
Matthew R. Lee
Dagart Allison
Xiao-Peng Yu
Srinivasan Chandrasekhar
Ryan T. Backer
Aiping Zhang
Marijane Russell
S. Chang
Anita K. Harvey
Ashley V. Sloan
Matthew Joseph Fisher
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Citations (47)
The 2.5 Å crystal structure of the SIRT1 catalytic domain bound to nicotinamide adenine dinucleotide (NAD+) and an indole (EX527 analogue) reveals a novel mechanism of histone deacetylase inhibition.
2013
Journal of Medicinal Chemistry
Xun Zhao
Dagart Allison
Bradley Condon
Feiyu Zhang
T. Gheyi
Aiping Zhang
Sheela Ashok
Marijane Russell
Iain MacEwan
Yuewei Qian
James A. Jamison
John G. Luz
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Citations (131)
Crystal structure of the SIRT1 catalytic domain bound to NAD and an EX527 analog
2013
X. Zhao
Dagart Allison
Bradley Condon
Feiyu Zhang
Tarun Gheyi
Aiping Zhang
Sheela Ashok
Marijane Russell
Iain MacEwan
Yuewei Qian
J. A. Jamison
John G. Luz
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