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David M. Duda

St. Jude Children's Research Hospital

31

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3018

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Structural Studies of HHARI/UbcH7∼Ub Reveal Unique E2∼Ub Conformational Restriction by RBR RING1

2017 Structure
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Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation

2016 Cell
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Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy

2015 Proceedings of the National Academy of Sciences of the United States of America
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Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis

2014 Molecular Cell
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TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin‐RING ligase complexes

2013 The EMBO Journal
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Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism.

2013 Structure
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Crystal structure of Atg7 NTD K14A F16A D18A mutant

2012
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Crystal structure of an Atg7-Atg10 crosslinked complex

2012
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Structure of a Glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface

2012 Molecular Cell
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The Glomuvenous Malformation Protein Glomulin Binds Rbx1 and Regulates Cullin RING Ligase-Mediated Turnover of Fbw7

2012 Molecular Cell
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