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Tiffany N. Seagroves

University of Tennessee Health Science Center

77

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HIF-dependent expression of creatine kinase brain isoform (CKB) promotes breast cancer metastasis, and blocking creatine kinase activity with cyclocreatine impairs invasion and improves the efficacy of conventional chemotherapies

2021 bioRxiv
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Design, Synthesis, and Biological Evaluation of Stable Colchicine-Binding Site Tubulin Inhibitors 6-Aryl-2-benzoyl-pyridines as Potential Anticancer Agents.

2021 Journal of Medicinal Chemistry
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Abstract PS11-37: Veru-111 as an orally available tubulin inhibitor suppressing both taxane-sensitive and taxane-resistant triple-negative breast cancer

2021 Cancer Research
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VERU-111: An Oral Tubulin Inhibitor That Suppresses Taxane-Sensitive and Taxane-Resistant Breast Cancer

2021 Journal of the Endocrine Society
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Heterotypic clustering of circulating tumor cells and circulating cancer-associated fibroblasts facilitates breast cancer metastasis

2021 Breast Cancer Research and Treatment
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HIF-dependent CKB expression promotes breast cancer metastasis, whereas cyclocreatine therapy impairs cellular invasion and improves chemotherapy efficacy

2021 bioRxiv
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Abstract 3071: VERU-111, a novel orally bioavailable tubulin inhibitor, overcomes taxane resistance in metastatic triple-negative breast cancer

2020 Cancer Research
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Pivarubicin is more effective than doxorubicin against triple-negative breast cancer in vivo.

2020 Oncology Research
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Breast tumor kinase (Brk/PTK6) mediates advanced cancer phenotypes via SH2-domain dependent activation of RhoA and aryl hydrocarbon receptor (AhR) signaling

2020 Molecular Cancer Research
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"Making the Right Decisions: Adapting to Emerging Needs": The 7th Annual Meeting of the Southeastern Association of Shared Resources, Atlanta, GA, USA, June 12-14, 2019.

2020 Journal of biomolecular techniques
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