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Laura A. Novotny

The Research Institute at Nationwide Children's Hospital
Ohio State University
Nationwide Children's Hospital

53

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1628

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Humanized Anti-DNABII Fab Fragments Plus Ofloxacin Eradicated Biofilms in Experimental Otitis Media.

2021 Laryngoscope
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Z-form extracellular DNA is a structural component of the bacterial biofilm matrix

2021 Cell
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The extracellular innate-immune effector HMGB1 limits pathogenic bacterial biofilm proliferation.

2021 Journal of Clinical Investigation
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Transcutaneous immunization with a nontypeable Haemophilus influenzae dual adhesin-directed immunogen induces durable and boostable immunity

2020 Vaccine
- Laura A. Novotny
- Lauren O. Bakaletz
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Targeting a bacterial DNABII protein with a chimeric peptide immunogen or humanised monoclonal antibody to prevent or treat recalcitrant biofilm-mediated infections.

2020 EBioMedicine
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Nontypeable Haemophilus influenzae newly released (NRel) from biofilms by antibody-mediated dispersal versus antibody-mediated disruption are phenotypically distinct

2020 Biofilms
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Nontypeable Haemophilus influenzae Type IV pilus mediates augmented adherence to rhinovirus-infected human airway epithelial cells.

2020 Infection and Immunity
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Immunization with a Biofilm-Disrupting Nontypeable Haemophilus influenzae Vaccine Antigen Did Not Alter the Gut Microbiome in Chinchillas, Unlike Oral Delivery of a Broad-Spectrum Antibiotic Commonly Used for Otitis Media.

2020
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Nontypeable Haemophilus influenzae Responds to Virus-Infected Cells with a Significant Increase in Type IV Pilus Expression.

2020
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Biofilm Biology and Vaccine Strategies for Otitis Media Due to Nontypeable Haemophilus influenzae

2019 Journal of Pediatric infectious diseases
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