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Yesim Altas Tahirovic

Emory University

18

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221

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A GluN2B-selective inhibitor of NMDA receptor function with enhanced potency at acidic pH and oral bioavailability for clinical use.

2021 Journal of Pharmacology and Experimental Therapeutics
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Amino-Heterocycle Tetrahydroisoquinoline CXCR4 Antagonists with Improved ADME Profiles via Late-Stage Buchwald Couplings

2021 ACS Medicinal Chemistry Letters
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Small molecule and peptide-based CXCR4 modulators as therapeutic agents. A patent review for the period from 2010 to 2018.

2020 Expert Opinion on Therapeutic Patents
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Design, Synthesis, and Pharmacological Evaluation of Second-Generation Tetrahydroisoquinoline-Based CXCR4 Antagonists with Favorable ADME Properties

2018 Journal of Medicinal Chemistry
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Synthesis of Novel Tetrahydroisoquinoline CXCR4 Antagonists with Rigidified Side-chains

2018 ACS Medicinal Chemistry Letters
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Discovery of Tetrahydroisoquinoline-Containing CXCR4 Antagonists with Improved in Vitro ADMET Properties

2018 Journal of Medicinal Chemistry
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Synthesis and SAR of 1,2,3,4-Tetrahydroisoquinoline-Based CXCR4 Antagonists

2018 ACS Medicinal Chemistry Letters
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Author response: An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups

2018 eLife
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An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups

2018 eLife
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Discovery of N-Alkyl Piperazine Side Chain Based CXCR4 Antagonists with Improved Drug-like Properties

2018 ACS Medicinal Chemistry Letters
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