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Alex G. Therien

Merck & Co.

24

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646

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Immunomodulation by the Commensal Microbiome During Immune-Targeted Interventions: Focus on Cancer Immune Checkpoint Inhibitor Therapy and Vaccination

2021 Frontiers in Immunology
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SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development.

2021 PLOS Pathogens
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The impact of DAMP-mediated inflammation in severe COVID-19 and related disorders.

2021 Biochemical Pharmacology
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Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab

2017 Journal of Molecular Biology
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Functional defects in Clostridium difficile TcdB toxin uptake identify CSPG4 receptor-binding determinants

2017 Journal of Biological Chemistry
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Toxin-Mediated Paracellular Transport of Antitoxin Antibodies Facilitates Protection against Clostridium difficile Infection

2015 Infection and Immunity
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Broad Coverage of Genetically Diverse Strains of Clostridium difficile by Actoxumab and Bezlotoxumab Predicted by In Vitro Neutralization and Epitope Modeling

2015 Antimicrobial Agents and Chemotherapy
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Mechanisms of protection against Clostridium difficile infection by the monoclonal antitoxin antibodies actoxumab and bezlotoxumab.

2015 Infection and Immunity
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Correction for Zhang et al., Toxin-Mediated Paracellular Transport of Antitoxin Antibodies Facilitates Protection against Clostridium difficile Infection

2015 Infection and Immunity
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Small Molecule Inhibitors of Clostridium difficile Toxin B-Induced Cellular Damage

2015 Chemistry & Biology
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