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Patrick F. Smith

Hoffmann-La Roche
University at Buffalo
Roswell Park Cancer Institute

89

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2426

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Respiratory syncytial virus-A dynamics and the effects of lumicitabine, a nucleoside viral replication inhibitor, in experimentally infected humans

2019 Journal of Antimicrobial Chemotherapy
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Cost-utility analysis of antiviral use under pandemic influenza using a novel approach - Linking pharmacology, epidemiology and heath economics

2018 Epidemiology and Infection
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A pharmacokinetic/viral kinetic model to evaluate treatment of chronic HCV infection with a non-nucleoside polymerase inhibitor

2018 Antiviral Therapy
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Interdisciplinary pharmacometrics linking oseltamivir pharmacology, influenza epidemiology and health economics to inform antiviral use in pandemics

2017 British Journal of Clinical Pharmacology
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A Phase I Trial of PRN1008, A Novel Reversible Covalent Inhibitor of Bruton's Tyrosine Kinase, In Healthy Volunteers

2017 British Journal of Clinical Pharmacology
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A new treatment for autoimmune blistering diseases- the efficacy of Bruton's tyrosinase kinase inhibitor PRN473 in canine pemphigus foliaceus

2016
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A phase 1, multicenter, dose-escalation study of PRN1371, an irreversible covalent FGFR1-4 kinase inhibitor, in patients with advanced solid tumors, followed by expansion cohorts in patients with FGFR genetic alterations.

2016 Journal of Clinical Oncology
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Erratum for Kamal et al., A Drug-Disease Model Describing the Effect of Oseltamivir Neuraminidase Inhibition on Influenza Virus Progression.

2016 Antimicrobial Agents and Chemotherapy
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Safety and Pharmacokinetics of the Respiratory Syncytial Virus Polymerase Inhibitor, ALS-8176, in Otherwise Healthy Infants Hospitalized with Acute RSV Infection

2016 Open Forum Infectious Diseases
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THU0068 Preclinical Characterization of PRN1008, a Novel Reversible Covalent Inhibitor of BTK that Shows Efficacy in a RAT Model of Collagen-Induced Arthritis

2015 Annals of the Rheumatic Diseases
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