Mangiferin

Mangiferin is a xanthonoid. This molecule is a glucoside of norathyriol. Mangiferin is a xanthonoid. This molecule is a glucoside of norathyriol. Mangiferin was first isolated from the leaves and bark of Mangifera indica. It can also be extracted from mango peels and kernels, Iris unguicularis, Anemarrhena asphodeloides rhizomes and Bombax ceiba leaves. It is also found in the genera Salacia and Cyclopia. Among the group of Asplenium hybrids known as the 'Appalachian Asplenium complex', mangiferin and isomangiferin are produced only by Asplenium montanum and its hybrid descendants. The distinctive gold-orange fluorescence of these compounds under ultraviolet light has been used to aid in the chromatographic identification of hybrid Aspleniums. Laboratory studies have identified a variety of potential pharmacology-associated properties of mangiferin, including antimicrobial and antioxidant activities, inhibitory effects on type II 5α-reductase in vitro, and gastroprotective and antidiabetic effects in rodents.