SEC23A

Sec23 homolog A (S. cerevisiae), also known as SEC23A, is a protein which in humans is encoded by the SEC23A gene.2NUP, 2NUT, 2YRC, 2YRD, 3EFO, 3EG9, 3EGD, 3EGX1048420334ENSG00000100934ENSMUSG00000020986Q15436Q01405NM_006364NM_009147NM_001361956NP_006355NP_033173NP_001348885The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It contains a gelsolin domain. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking.SEC23A has been shown to interact with SEC24C, Sec16A/p250 and iPLA1β/p125.