Interleukin 19

1N1F29949329244ENSG00000142224ENSMUSG00000016524Q9UHD0Q8CJ70NM_013371NM_153758NM_001369605NM_001009940NM_001355135NP_037503NP_715639NP_001356534NP_001009940NP_001342064Interleukin 19 (IL19) is a protein that in humans is encoded by the IL19 gene on the chromosome 1. Interleukin 19 (IL19) is a protein that in humans is encoded by the IL19 gene on the chromosome 1. The IL-19 gene contains 7 exons and is found on chromosome 1. Secreted IL-19 is made from 159 amino acids that create alpha-helix structure. The protein encoded by this gene is a cytokine that belongs to the IL-10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes and less in B lymphocytes. The IL-19 gene is expressed in resting monocytes and B cells. It is up-regulated in monocytes following stimulation with granulocyte-macrophage colony-stimulating factor (GM-CSF), lipopolysaccharide, or Pam3CSK4.