SCN3A

632820269ENSG00000153253ENSMUSG00000057182Q9NY46A2ASI5NM_001081676NM_001081677NM_006922NM_001355170NM_001355171NP_001075145NP_001075146NP_008853NP_001342100NP_061202Sodium channel, voltage-gated, type III, alpha subunit (SCN3A) is a protein that in humans is encoded by the Nav1.3 gene.1byy: SODIUM CHANNEL IIA INACTIVATION GATE Sodium channel, voltage-gated, type III, alpha subunit (SCN3A) is a protein that in humans is encoded by the Nav1.3 gene. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. SCN3A is involved in folding the human cerebral cortex, a process called 'gyrification', and affects speech production brain areas. This article incorporates text from the United States National Library of Medicine, which is in the public domain.