FHL1

1X63, 2CUP, 2CUR227314199ENSG00000022267ENSMUSG00000023092Q13642Q5JXH9P97447NM_001159704NM_001167819NM_001449NM_001330659NM_001369326NM_001369327NM_001369328NM_001369329NM_001369330NM_001369331NM_001077361NM_001077362NM_001287800NM_010211NP_001153176NP_001161291NP_001317588NP_001440NP_001356255NP_001356256NP_001356257NP_001356258NP_001356259NP_001356260NP_001070829NP_001070830NP_001274729NP_034341Four and a half LIM domains protein 1 is a protein that in humans is encoded by the FHL1 gene.1x63: Solution structure of the second LIM domain of skeletal muscle LIM protein 12cup: Solution structure of the Skeletal muscle LIM-protein 12cur: Solution structure of Skeletal muscle LIM-protein 1 Four and a half LIM domains protein 1 is a protein that in humans is encoded by the FHL1 gene. LIM proteins, named for 'LIN11, ISL1, and MEC3,' are defined by the possession of a highly conserved double zinc finger motif called the LIM domain. FHL1 has been shown to be heavily expressed in skeletal and cardiac muscles. In 2008 this was borne out by the discovery that defects in the FHL1 gene are responsible for a number of Muscular dystrophy-like muscle disorders, ranging from severe, childhood onset diseases through to adult-onset disorders similar to Limb girdle muscular dystrophy. At present different research groups are using different terminology for these disorders, which include: This article incorporates text from the United States National Library of Medicine, which is in the public domain.