EMAGE

EMAGE (e-Mouse Atlas of Gene Expression) is an online biological database of gene expression data in the developing mouse (Mus musculus) embryo. The data held in EMAGE is spatially annotated to a framework of 3D mouse embryo models produced by EMAP (e-Mouse Atlas Project). These spatial annotations allow users to query EMAGE by spatial pattern as well as by gene name, anatomy term or Gene Ontology (GO) term. EMAGE is a freely available web-based resource funded by the Medical Research Council (UK) and based at the MRC Human Genetics Unit in the Institute of Genetics and Molecular Medicine, Edinburgh, UK. EMAGE (e-Mouse Atlas of Gene Expression) is an online biological database of gene expression data in the developing mouse (Mus musculus) embryo. The data held in EMAGE is spatially annotated to a framework of 3D mouse embryo models produced by EMAP (e-Mouse Atlas Project). These spatial annotations allow users to query EMAGE by spatial pattern as well as by gene name, anatomy term or Gene Ontology (GO) term. EMAGE is a freely available web-based resource funded by the Medical Research Council (UK) and based at the MRC Human Genetics Unit in the Institute of Genetics and Molecular Medicine, Edinburgh, UK. EMAGE contains in situ hybridisation, immunohistochemistry, and in situ reporter (e.g. knock-in and gene trap) data. It includes wholemount data, section data and full 3D OPT (Optical Projection Tomography) data. The gene expression patterns are mapped into or onto the standard models by a team of biocurators, using bespoke mapping software. In addition to the spatial annotations, EMAGE data is also text annotated to provide a text based description of the expression patterns. This text annotation is carried out in collaboration with the MGI Gene Expression Database (GXD) using the EMAP mouse anatomy ontology.