RBX1

1LDJ, 1LDK, 1U6G, 2HYE, 2LGV, 3DPL, 3DQV, 3RTR, 4F52, 4P5O9978100043674ENSG00000100387n/aP62877n/aNM_014248XM_006525232XM_006536722XM_006537452NP_055063n/aRING-box protein 1 is a protein that in humans is encoded by the RBX1 gene.1ldj: Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex1ldk: Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex1u6g: Crystal Structure of The Cand1-Cul1-Roc1 Complex2hye: Crystal Structure of the DDB1-Cul4A-Rbx1-SV5V Complex RING-box protein 1 is a protein that in humans is encoded by the RBX1 gene. This gene encodes an evolutionarily conserved protein that interacts with cullins. The protein plays a unique role in the ubiquitination reaction by heterodimerizing with cullin-1 to catalyze ubiquitin polymerization. It also may be involved in the regulation of protein turn-over. RBX1 has been shown to interact with: