Platelet-activating factor receptor

2B0X572419204ENSG00000169403ENSMUSG00000056529P25105Q62035NM_001164723NM_000952NM_001164721NM_001164722NM_001081211NP_000943NP_001158193NP_001158194NP_001158195NP_001074680The platelet-activating factor receptor is a G-protein coupled receptor which binds platelet-activating factor. The platelet-activating factor receptor is a G-protein coupled receptor which binds platelet-activating factor. The PAF receptor shows structural characteristics of the rhodopsin (MIM 180380) gene family and binds platelet-activating factor (PAF). PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes. Its pathogenetic role in chronic kidney failure has also been reported recently. Agonists Antagonists This article incorporates text from the United States National Library of Medicine, which is in the public domain.