Gap-43 protein

4E53259614432ENSG00000172020ENSMUSG00000047261P17677P06837NM_002045NM_001130064NM_008083NP_001123536NP_002036NP_032109Growth Associated Protein 43 (GAP43) is a protein encoded by the GAP43 gene in humans. Growth Associated Protein 43 (GAP43) is a protein encoded by the GAP43 gene in humans. GAP43 is called a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration, and it is phosphorylated after long-term potentiation and after learning. GAP43 is a crucial component of the axon and presynaptic terminal. Its null mutation leads to death within days after birth, due to axon pathfinding defects.