Sudomotor (from Latin sudor, 'sweat' and motor) describes anything that stimulates the sweat glands. Sudomotor (from Latin sudor, 'sweat' and motor) describes anything that stimulates the sweat glands. Sudomotor innervation is the cholinergic innervation of the sympathetic nervous system prominent in sweat glands which causes perspiration to occur via activation of muscarinic acetylcholine receptors. Release of acetylcholine and nitric oxide induced vasodilation occur. Increased blood flow causes more sweat and also allows heat loss via skin.