EphrinB2 controls vessel pruning through STAT1-JNK3 signalling
2015
Pruningof newly formed blood vessels is an important and yet poorly understood aspect of angiogenesis. Here the authors show that endothelial phosphotyrosine-dependent EphrinB2 signalling represses JNK3 function via
STAT1, and identify JNK3 as an effector of endothelial cell death and vessel
pruningin mice.
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