Criteria for the Selection of a Proper Enantiomer-Selective Analytical Method

During the past two decades and after the first edition of this monograph was published in 2001, tremendous progress has been made with respect to sensitivity and selectivity in scientific technology for ultra-trace analysis. Today, chromatographic separation and modern mass-selective detection have been significantly improved as compared with the earlier methods introduced during the first edition. High-resolution liquid chromatography today is the separation method of choice for enantiomer-selective separation of many chiral environmental toxicants (Huhnerfuss and Shah 2009; Kasprzyk-Hordern 2010; Lehmler et al. 2010; Li et al. 2010; Nillos et al. 2010; Ali et al. 2012; Brooks et al. 2012; Ulrich et al. 2012; Kania-Korwel and Lehmler 2016; Basheer 2017; Guo et al. 2017; Peluso et al. 2017). Many updated monographs, books and reviews are today illustrating the versatility of enantiomer-selective analytical methods, not just for environmental pollutant research (Inoue and Ramamurthy 2004; Reddy and Miḥvar 2004; Francotte and Lindner 2006; Subramanian 2007; Eeckhaut and Michotte 2009; Berthod 2010; Cutillas and Timms 2010; Dasgupta 2010; Busch and Busch 2011; Garrison et al. 2011; Lin et al. 2011).