Synthesis of the Novel Tetrahydropyrazolo[3,4-c]pyridin-5-one Scaffold

We report an efficient synthesis of the novel 1,4,6,7-tetra­hydropyrazolo[3,4- c ]pyridin-5-one scaffold with the potential for incorporation of alkyl or aryl substituents at the C-3 and N-6 positions. The route utilises a Dieckmann condensation to install the lactam ring, followed by a hydrazine cyclisation to build the fused pyrazole ring.