Efficacy of lamotrigine in idiopathic generalized epilepsy syndromes: a video-EEG-controlled, open study

During the last few years many new antiepileptic drugs (AED) have been marketed to treat epilepsy refractory to classic AED. Nevertheless, clinical development is principally designed for licensing and not for clinical practice use. So a majority of trials are of little value in terms of treatment choice in a given patient [1]. Lamotrigine (LTG) is licensed in about 80 countries as add-on therapy in severe refractory epilepsy. Placebo-controlled, [...]