Exosomes as Hedgehog carriers in cytoneme-mediated transport and secretion
2014
Long, thin projections of the cell membrane known as cytonemes are required for signalling by the secreted morphogen Hedgehog. Gradilla et al. show that cytonemes carry Hedgehog-associated exovesicles, and that exovesicle formation is required for graded Hedgehog signalling.
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