Effect of detection of epigenomic changes in plasma-derived cell-free DNA on multicancer classification.

Anna Bergamaschi,David Haan,Jeremy Ku,Yuhong Ning,Christopher E. Ellison,Gulfem Guler,Tierney Phillips,Erin McCarthy,Michaël Antoine,Albert Nguyên,Aaron Scott,Paul Lloyd,Alan Ashworth,Kelly Bethel,Samuel Levy

Effect of detection of epigenomic changes in plasma-derived cell-free DNA on multicancer classification.

2020

Anna Bergamaschi
David Haan
Jeremy Ku
Yuhong Ning
Christopher E. Ellison
Gulfem Guler
Tierney Phillips
Erin McCarthy
Michaël Antoine
Albert Nguyên
Aaron Scott
Paul Lloyd
Alan Ashworth
Kelly Bethel
Samuel Levy

1539Background: Epigenomic changes in DNA methylation patterns are more precisely delineated by active demethylation events as marked by 5-hydroxymethylation (5hmC) of cytosine residues. 5hmC appea...

Keywords:

Epigenomics
plasma derived
Pathology
Cell biology
Cell-free fetal DNA
Medicine
Demethylation
Cytosine
Molecular biology
DNA methylation

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