Digital colposcopy for the diagnosis of cervical adenocarcinoma using a narrow band imaging system.
2010
Introduction: Although the
colposcopicfeatures of cervical glandular disease and
cervical adenocarcinomaare not widely well known, unique microvascular patterns are reportedly useful for identifying such diseases. The
narrow band imaging(NBI) system used in endoscopy can be used to obtain high-contrast vascular images. Therefore, we examined the utility of NBI
colposcopyand compared the results with those of conventional
colposcopy. Methods: Twenty-one patients with adenocarinoma in situ or early invasive
adenocarcinomaswere examined using digital NBI
colposcopy, and the photo records were compared with those of conventional
colposcopy. The histological examination and immunohistochemistry with anti-
CD31antibody confirmed the microvascular pattern. Results: Digital NBI
colposcopydepicted the fine vascular texture on the surface of the cervix more clearly than conventional
colposcopy. The vascular pattern was depicted in 86% (18/21) of glandular disease cases. The characteristic fine vascular patterns were critical for identifying cervical glandular diseases. Conclusions: Digital NBI
colposcopywas useful for identifying early
cervical adenocarcinomaas well as
adenocarcinomain situ. This system yields cervical glandular disease-related
colposcopicfindings that may be useful for both clinical and educational purposes.
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