Antigen 5–spiked Vespula and Polistes venom extracts for Vespid allergy diagnostics: A French multicenter study

Vespula and Polistes spp venom extracts (VEs) for ImmunoCAP (Thermo Fisher Scientific, Uppsala, Sweden) platforms have been spiked, that is, enriched, with group 5 allergens since 2012. Limited information was available from the manufacturer, but small cohorts have reported altered performance for in vitro diagnostics.1,2 Herein we present the results of a French multicenter study on antigen 5–spiked Vespula and Polistes VEs compared with nonspiked VEs