Haematobiochemical and serum electrolytes alteration in dogs with chronic kidney disease

Dogs with progressive chronic kidney disease (CKD) have haematological alteration of different intensities reflected on the complete blood count parameters. The purpose of this study was to evaluate changes in haemato-biochemical and electrolyte parameters in dogs with CKD. The present study was conducted on 30 dogs suffering from CKD. Major alteration in hematological profile were overall lower levels of hemoglobin (9.15 ± 0.67 g/dl), TEC (4.47 ± 0.30 x 106/mm3), PCV (29.22 ± 2.05 %) values and platelet count (196.23 ± 18.31x 103/µL) in all the affected dogs. Affected dogs were showing higher mean TLC count and percentage lymphocytes as compared to reference values. All affected dogs were showing azotemia of various degrees along with mean values of alkaline phosphatase towards higher side (112.65 ± 21.61 U/L), GGT (11.79 ± 1.47 U/L), hyperphosphatemia (11.25 ± 1.17 mg/dl), hyponatremia (140.96 ± 1.69 mmol/L), slight hyperkalemia (5.13 ± 0.22 mmol/L), hypocalcaemia (8.93 ± 0.43 mg/dl). Complete blood count and serum characteristics in CKD provides useful information about the progress of the disease as well as anemia type appreciation offering additional information for therapeutic protocol adjustment for amelioration of induced haemato-biochemical and electrolyte consequences.