Screening of CHEK2 and TP53 p.R337H germ-line mutations in high-risk patients for hereditary breast and ovarian cancer from northeast of Brazil.
2017
1539 Background:
CHEK2is a molecular messenger that interacts with a checkpoint network of other susceptibility genes like ATM, BRCA1, TP53,
MDM2,
Cdc25Aand Cdc25C. The mission of these checkpoin...
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