Prizadetost pljuč in srca po obsevanju ter kemoterapiji Hodgkinove bolezni

Acute and chronic defects following childhood cancer treatment are rare with modern treatment techniques and usually without any clinical signs and symptoms. In a patient who was treated for childhood Hodgkin's lymphoma with irradiation to the neck, supraclavicular lymph nodesand mediastinumand chemotherapy, the consequences include a probable combination of adverse effects of this treatment on the lungs and heart. Considering the course and progression of lung impairment, vascular impairment - pulmonary vasculopathy was found to be at the forefront in our patient, which was confirmed by histological examination of the lung-tissue bioptat. By describing this case, we wish to point to the chronic and progredient course of the disease which requires complex managementby specialists and causes severe disability 22 years after treatment.