Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

Han Jw,Hou-Feng Zheng,Yong Cui,Sun Ld,Ye Dq,Hu Z,Jinhua Xu,Zhiming Cai,Wei Huang,Guoping Zhao,Xie Hf,Hong Fang,Lu Qj,Xiangpei Li,Yunfeng Pan,Deng Dq,Zeng Fq,Ye Zz,X Y Zhang,Wang Qw,Fei Hao,Ma L,Zuo Xb,Fusheng Zhou,Du Wh,Cheng Yl,Yang Jq,Shen Sk,Li J,Yujun Sheng,Zuo Xx,Zhu Wf,Gao F,Zhang Pl,Guo Q,Li B,Min Gao,Feng-Li Xiao,Cheng Quan,Chi Zhang,Zhang Z,Zhu Kj,Yi Li,Hu Dy,Wei Lu,Jianlin Huang,Liu Sx,Li H,Yunqing Ren,Zaixing Wang,Yang Cj,Wang Pg,Zhou Wm,Lv Ym,Zhang Ap,Zhang Sq,Lin D,Hui-Qi Low,Min Shen,Zhai Zf,Yuezhu Wang,Zhang Fy,Sen Yang,Jianjun Liu,X.J. Zhang

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

2009

Xuejun Zhang and colleagues report results of a genome-wide association study of systemic lupus erythematosus (SLE) in a Chinese Han population. Their work identifies nine new SLE susceptibility loci and reveals overlap in the spectrum of risk alleles shared between Chinese Han and European populations.

Keywords:

Genetics
Lupus erythematosus
Locus (genetics)
Allele
Systemic disease
Genotype
Genome-wide association study
Single-nucleotide polymorphism
Population
Biology
Connective tissue disease
Zhàng
Genome

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