Assessment of Behavioral Approach and Behavioral Inhibition Systems in Mood Disorders
2018
Introduction: Psychiatric disorders could be evaluated in terms of behavioral activation and
inhibition systems. Dysregulation of these systems may lead to development of manic or
depressive episodes in patients with mood disorders. This study aimed to identify Behavioral
Approach System (BAS) and Behavioral Inhibition System (BIS) hypersensitivity as the
functional brain system behaviors in patients with major depressive disorder and bipolar mood
disorder I, compared to healthy individuals.
Methods: This case-control study was conducted in Razi Psychiatric Hospital, a mental health
referral center in Northwest of Iran. The study consisted of two groups of patients, one with
major depressive and the other with bipolar mood disorders and one healthy group. Each group
had 40 patients (20 men and 20 women). The study data were collected through BIS and BAS
questionnaire, Beck Depression Inventory (BDI-II), Young Mania Rating Scale (YMRS). The
obtained data were analyzed by SPSS version 18.
Results: The findings showed a significant negative correlation between BIS, BAS
and BAS subscales with the severity of depression and positive correlation with mania
symptoms (P<0.05).
Conclusion: BAS and BIS dysregulations may predispose people to mood disorder
symptoms. BAS is hyperactive during manic phase and may predict the symptom severity
of bipolar mood disorder.
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