Rapport et recommandations sur la mise en œuvre en France des techniques de séquençage de nouvelle génération

SUMMARY Next generation sequencing (NGS) technologies, which allow high speed automated DNA sequencing, DNA sequenceanalysis and comparisons using big data algorithms are being used more and more in medical diagnosis, to provide prognosis information and for choosing a treatment that best fits the patient. The French “Academie nationale de medecine ” (ANM) and “ Academie des technologies “ (NATF) jointly stress the scientific and medical importance of these technologies and call for bringing together strengths of the national computer science industry and the medical community in a public-private consortium in order to build a Demonstrator and Center network filling up the growing gap between France and the most advanced countries in this field with great potential. They underline also common pitfalls which need to be addressed in technic, legal, economic, educationand ethics issues, in order to make this complex project a success.