Reconstructions of refractive index tomograms via discrete algebraic reconstruction technique

2017
Optical diffraction tomography(ODT) provides three-dimensional refractive index (RI) tomograms of a transparent microscopic object. However, because of the finite numerical apertureof objective lenses, ODT has the limited access to diffracted light and suffers from poor spatial resolution, particularly along the axial direction. To overcome the limitation of the resolution and the quality of RI tomography, we present an algorithm that accurately reconstructs RI tomographyusing preliminary information that the RI values of a specimen are discrete and uniform. Through simulations and experiments on various samples, including microspheres, red blood cells, and water droplets, we show that the proposed method can precisely reconstruct RI tomograms of samples with discrete and uniform RI values in the presence of the missing information and noise.
    • Correction
    • Cite
    • Save
    0
    References
    0
    Citations
    NaN
    KQI
    []
    Baidu
    map