Reconstructions of refractive index tomograms via discrete algebraic reconstruction technique
2017
Optical
diffraction tomography(ODT) provides three-dimensional refractive index (RI) tomograms of a transparent
microscopic object. However, because of the finite
numerical apertureof objective lenses, ODT has the limited access to diffracted light and suffers from poor spatial resolution, particularly along the axial direction. To overcome the limitation of the resolution and the quality of RI
tomography, we present an algorithm that accurately reconstructs RI
tomographyusing preliminary information that the RI values of a specimen are discrete and uniform. Through simulations and experiments on various samples, including microspheres, red blood cells, and water droplets, we show that the proposed method can precisely reconstruct RI tomograms of samples with discrete and uniform RI values in the presence of the missing information and noise.
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