Phase I/II Study of Palliative Triple Metronomic Chemotherapy in Platinum-Refractory/Early-Failure Oral Cancer

Vijay Patil,Vanita Noronha,Amit D. Joshi,Sachin Dhumal,Manoj B. Mahimkar,Atanu Bhattacharjee,Vikram Gota,Manish Kumar Pandey,Nandini Menon,Abhishek Mahajan,Nilesh Sable,Suman Kumar,Kavita Nawale,Sadaf A. Mukadam,Bhavin Solanki,Sudeep Das,Vijai Simha,George Abraham,Arun Chandrasekharan,Vikas Talreja,Hollis D'Souza,S. Srinivas,Lakhan Kashyap,Shripad Banavali,Kumar Prabhash

Phase I/II Study of Palliative Triple Metronomic Chemotherapy in Platinum-Refractory/Early-Failure Oral Cancer

2019

PURPOSEPlatinum-resistant oral cancer has a dismal outcome with limited treatment options. We conducted a phase I/II study to identify the optimal biologic dose (OBD) of methotrexatewhen given alo...

Keywords:

Oncology
Methotrexate
Pathology
Refractory
Cancer
Metronomic Chemotherapy
Internal medicine
Medicine
treatment options
platinum resistance
early failure
phase i ii

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