Functional Calsequestrin-1 Is Expressed in the Heart and Its Deficiency Is Causally Related to Malignant Hyperthermia-Like Arrhythmia.

Zhipeng Sun,Lu-qi Wang,Lu Han,Yue Wang,Yuan Zhou,Qiang Li,Yongquan Wu,Shaletanati Talabieke,Yunlong Hou,Lulin Wu,Ronghua Liu,Zhiping Fu,Hongjie You,Bai-Yan Li,Yuanyuan Zheng,Dali Luo

Functional Calsequestrin-1 Is Expressed in the Heart and Its Deficiency Is Causally Related to Malignant Hyperthermia-Like Arrhythmia.

2021

Zhipeng Sun
Lu-qi Wang
Lu Han
Yue Wang
Yuan Zhou
Qiang Li
Yongquan Wu
Shaletanati Talabieke
Yunlong Hou
Lulin Wu
Ronghua Liu
Zhiping Fu
Hongjie You
Bai-Yan Li
Yuanyuan Zheng
Dali Luo

Background: Calsequestrins (Casqs), comprising the Casq1 and Casq2 isoforms, buffer Ca2+ and regulate its release in the sarcoplasmic reticulum (SR) of skeletal and cardiac muscle, respectively. Hu...

Keywords:

Internal medicine
Calsequestrin
Medicine
volatile anesthetic
Endoplasmic reticulum
Cardiac muscle
Endocrinology
Malignant hyperthermia
Gene isoform

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