Ectodermal dysplasia: Case report and molecular review

The term ‘Ectodermal dysplasia’ refers to a group of heterogenous hereditary disorders characterized by abnormalities in ectodermal derivatives. There have been a number of classifications over time for ectodermal dysplasias given its varied presentation. However, the recent clinical-functional classification by Priolo has given due cognizance to the biopathogenetic mechanisms of this disorder. This paper presents a case report of hypohidrotic ectodermal dysplasia and focuses on the various genes and their pathways identified in the past decade.