Small vessel occlusion is a high-risk etiology for early recurrent stroke after transient ischemic attack:

BackgroundRecent prospective registration studies of transient ischemic attackin Western countries demonstrated that large artery atherosclerosis is the highest risk etiology for early stroke recurrence under urgent evaluation and treatment. On the other hand, some limited transient ischemic attackstudies from East Asian countries showed transient ischemic attackpatients due to small vessel occlusion were at a higher early stroke risk.AimsWe aimed to assess the risk for early stroke in small vessel occlusion-transient ischemic attackpatients in a Japanese large transient ischemic attackregistry.MethodsWe analyzed the data of a prospective Japanese transient ischemic attackregistry including 1320 transient ischemic attackpatients within seven days after onset. Small vessel occlusion-transient ischemic attackwas defined as the presence of lacunartransient ischemic attacksyndrome, without other etiologies. The outcome measure was recurrent stroke within 30 days after transient ischemic attack. The ...