Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked To Human Coronary Atherosclerosis

Rationale: B-1 cell-derived natural IgM antibodies against oxidation-specific epitopes (OSE) on low-density lipoproteinare anti-inflammatory and atheroprotective. Bone marrow (BM) B-1a cells contr...