The Treatment Effect of an ACE-Inhibitor Based Regimen with Perindopril in Relation to Beta-Blocker use in 29,463 Patients with Vascular Disease: a Combined Analysis of Individual Data of ADVANCE, EUROPA and PROGRESS Trials

Introduction In everyday practice, angiotensin converting enzymeinhibitors and beta-blockersare cornerstonetreatments in patients with (cardio-) vascular disease. Clear data that evaluate the effects of the combination of these agents on morbidity and mortality are lacking.