EP519 Cutaneous and muscular metastasis of an endometrial adenocarcinoma: a case report

Introduction/Background Endometrial cancer accounts for 6 to 7% of all women9s cancer. Most of them are diagnosed with localized early stage disease, explaining a high survival rate. Endometrial carcinoma rarely metastasis to the skin with a reported prevalence of 0.8% and to the muscle with a prevalence of 2%. Methodology We report a case a 72 years old woman treated in our department for a cutaneous and muscular metastasis of an endometrial carcinoma. We did a systematic review of the literature. Results We report a case of a 72 years old woman, gravida 1, para 1, postmenopausal for 22 years. She had a hysterectomy for an endometrioid adenocarcinoma grade 1 in February 2014. She was referred to our department, in December 2015, for an abdominal mass. Biopsy showed a metastatic localisation of the endometrial adenocarcinoma early treated. She underwent 3 courses of chemotherapy with carboplatin and taxoter. Then, she had a complete surgical resection. She presented, 11 months later, with a gradually enlarging new abdominal mass which measures 60 × 50 mm. it was of hard consistency adhering to the skin next to laparotomy scar. The new CT scan showed a voluminous 158 × 120 mm cutaneous mass invading rectus abdominal muscle with no other metastatic localisation. She underwent a complete surgical resection. There was no recurrence after surgery. Conclusion Although endometrial carcinoma is one of the most diagnosed cancer in women, cutaneous and muscular metastasis is very rare. This manifestation explains the absence of treatment consensus. This situation can be a challenging for the physician mostly with the poor associated prognosis. Disclosure Nothing to disclose.