Spiro-Substituted Piperidines as Neurokinin Receptor Antagonists. Part 1. Design and Synthesis of (.+-.)-N-[2-(3,4-Dichlorophenyl)-4-(spiro [isobenzofuran-1(3H),4′-piperidin]-1′-yl)butyl]-N-methylbenzamide, YM-35375, as a New Lead Com