Histogram analysis of amide proton transfer–weighted imaging: comparison of glioblastoma and solitary brain metastasis in enhancing tumors and peritumoral regions

Objectives Differentiation of glioblastomas(GBMs) and solitary brain metastases (SBMs) is an important clinical problem. The aim of this study was to determine whether amide proton transfer–weighted (APTW) imaging is useful for distinguishing GBMs from SBMs.