Abstract P403: Blood Pressure Differences Associated With OMNIHEART-like Lower Sodium Compared With Typical American Higher Sodium Nutrient Profile: INTERMAP USA

Background: The DASH-Sodium trial demonstrated beneficial effects on blood pressure (BP) of the DASH dietwith lower sodium intake, compared to typical American diet with higher sodium. The subsequent OMNIHEART trial reported additional benefits for BP by replacing carbohydrate in the DASH dietwith either protein or monounsaturated fats. Objective: Assess possible BP benefits of a lower sodium OMNIHEART-like diet in free-living Americans using two statistical methods: a linear OMNIHEART nutrient score, and a Bayesian approach comparing estimated BP levels with an OMNIHEART-like lower sodium nutrient profile (“OMNIHEART”) and with a typical American higher sodium profile (“Control”). Methods: Cross-sectional datainclude four 24-h dietary recalls, two timed 24-h urine collections, eight BP readings for 2,195 individuals ages 40-59 from the International Studyon Macro/Micronutrients and Blood Pressure (INTERMAP). An OMNIHEART score (with 9 nutrient targets, based on the protein arm of the trial) was calcu...