Abstract 16959: Cardiomyocyte-Restricted Inhibition of p53 Activity Exacerbates Late Stage Doxorubicin Cardiotoxicity in a Juvenile Mouse Model

Introduction: Doxorubicin(DOX) is an effective anti-cancer therapeutic which induces transient cardiotoxicy during acute drug delivery. Cardiotoxicityre-occurs in some patients years after drug t...