Molecular control of the NEMO family of ubiquitin-binding proteins
2013
Nuclear factor-κB (NF-κB) signalling is tightly regulated through ubiquitylation and phosphorylation of its components. Integral to this post-translational regulation is the polyubiquitin-binding protein NF-κB essential modulator (NEMO), which controls the modification of numerous NF-κB signalling proteins, such as the canonical IκB kinase (IKKs) and IKK-related kinases.
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