10 Persian herbal medicines used for brain health

Abstract Brain conditions including neurodegenerative and neuropsychiatric disorders are becoming more prevalent and have emerged as major health concerns worldwide. Currently available pharmaceuticals may be of limited efficacy and are associated with a range of adverse side effects. Traditional Persian Medicine (TPM) including Persian herbal medicine has been used for various brain disorders over centuries that can offer alternative viable options. In addition, Persian herbs can serve as a potential source for identifying novel pharmacological interventions. In this chapter, some of the most commonly used herbal medicines in TPM ancient literatures including Canon of Medicine are discussed and the evidences of their effectiveness from preclinical and clinical studies are summarized. Based on the current findings, TPM herbs have demonstrated therapeutic potential for the treatment of brains disorders; however, more research is needed to confirm their clinical effectiveness and to determine the underlying mechanisms of action.