P1296 : Blocking NMDA receptors prolongs survival in rats with acute liver failure by dual protective mechanisms in kidney and brain

were 1094.67±239.37mIU/ml. The difference in values between these groups was statistically significant(p = 0.004). There was a statistically significantdifference in total leucocyte count, serum creatinine, INR and cleaved CK18 M30 levels among those that survived vs expired. Multivariate analysisfound that all these independently predict mortality. A receiver operating characteristiccurve was drawn for the new score. The score found was compared with the King’s College criteriaand the MELD score, the new scoring system was found to have higher sensitivity and specificity for mortality compared with other standard prognostic markers in ALF, and has a better diagnostic accuracy (Table 1).