Compounds and methods to inhibit phosphate transport
2011
A compound having the following structure (I): ** Formula ** or a stereoisomer, prodrug or pharmaceutically acceptable salt thereof, wherein: A is: ** Formula ** X is substituted aryl or substituted heteroaryl; Y is halogen, optionally substituted alkylamino, optionally substituted alkoxy, optionally substituted thioalkyl, optionally substituted cycloalkyl, optionally substituted heterocyclyl, optionally substituted aryl, -O (optionally substituted cycloalkyl), -O (optionally substituted heterocyclyl) or -O (optionally substituted aryl ); and R1 is optionally substituted aryl or optionally substituted heteroaryl, wherein the prodrug is selected from acetate, formate and benzoate derivatives of alcohol or amide derivatives of amine functional groups.
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